In large bowl, combine ground beef, liquid smoke and barbecue seasoning. Mix well.
Divide the mixture into 8 equally sized balls. With your hands, flatten the ball and gradually mold into patties (use your fingers to press and shape, ensuring that the patties do not fall apart). Form into large patties, slightly larger in diameter than the buns (approximately 6-inch diameter). As the hamburgers cook, they will shrink to the right diameter for the buns.