John Wayne Casserole

John Wayne Casserole created by Karen P.

This one was different than the others I saw on here so thought I'd add it. I'd seen it on facebook. The individual who posted stated it was from a Mississippi Magazine

Ready In:



  • Heat oven to 325. Brown ground beef and add taco seasoning and water, according to packet instructions; set aside.
  • In a separate bowl, combine sour cream, mayonnaise, 4 ounces of cheddar cheese, and half of the onions; set aside.
  • Stir biscuit mix and water (directions on box) to form soft dough. Pat dough on the bottom and one-half-inch up the sides of an 9 x 13 inches greased casserole dish.
  • Saute remaining onions and bell peppers until slightly tender.
  • On top of biscuit mix, evenly distribute ingredients in the following order: ground beef, tomato slices, green peppers, onions, jalapeno peppers, sour cream mixture and end with remaining shredded cheese.
  • Bake for 30-40 minutes or until edges of dough are lightly browned.
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"This one was different than the others I saw on here so thought I'd add it. I'd seen it on facebook. The individual who posted stated it was from a Mississippi Magazine"

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  1. Patti V.
    the first time I made this I followed the recipe. it was fabulous and everyone from my dad to my 2 year old grandson loved it. i just put another one in the oven and this one i did tweak the recipe but only in the respect of using some of the things i wanted to get rid of from the fridge. last night i made tacos and chicken black bean quesadillas. i had some left over black beans so i sprinkled them on top of the tomato layer. i didn't have (nor do i care for) green peppers so i used orange/red/yellow mini peppers. i had half a fresh jalapeno left over from making salsa so i minced just a little and cooked that with the peppers and onions. i used just a bit because of the kids. lastly, i mixed the mayo, sour cream, green onions (about three chopped well) and the cheese altogether and spread that on the top. i did think about putting some black olives on top but decided not this time. the reason i put the last four ingredients together is that my dad mentioned the first time that it was too thick of a layer so i thought mixing it will make it a bit better for him. anything for dad! looking forward to trying it out but i am sure that it will be delish as the basic recipe was not changed with the addition of the black beans.
  2. Connie P.
    Just finished making this and it is DELICIOUS
  3. AndreaTN
    There is a B&B in South Dakota that serves this, but they use tater tots, it is fast and easy. I dice up potatoes and use those instead to save on calories and going to try substituting cream of mushroom soup for the mayo and see how that works out.
  4. macklove21
    This is delicious! It was a huge hit with the family. I did cook the peppers and onions until they were almost caramelized and omitted the jalapenos on half of the casserole for the little ones. The biscuit base makes a perfect tex-mex dish. Will use again!
  5. the Vet
    This person is worried about the carbs when there is a ton of fat in this recipe? dump the mayo and use lite sour cream!

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