Cook noodles according to package directions. Remove from heat and drain. Return noodles to pot. Add remaining ingredients and mix well.
Spray 9x9-inch casserole pan with non-stick cooking spray. Place tuna noodle mixture in casserole dish.
Bake for 45 minutes.
While casserole is baking, process bread in food processor to obtain fine crumbs. Melt butter and pour over bread crumbs. Toss to coat. Remove casserole from oven after 30 minutes, top with buttered crumbs and continue to bake the final 15 minutes.