We use a Smokenator and Mesquite chips to smoke these boneless skinless breasts. The buttermilk marinade keeps them super moist and juicy without having do an entire chicken or even bone-in skin-on breasts. I am sure it would work just as well with either, though smoking times would definitely have to be increased. The chicken breasts that I have used were huge, so if yours are not as thick, check them sooner. You can also change up the herbs to your liking. Marinating time is not included in the prep time.