Heat a skillet over medium high heat. Add fresh breadcrumbs, cook 3 minutes or until toasted, stirring frequently.
While the breadcrumbs cook, heat a large skillet over medium high heat. Coat the pan with cooking spray. Add the onion and garlic; saute 3 minutes.
Combine onion mixture, breadcrumbs, 1/4 cup ketchup, and remaining ingredients. Shape into 6 (4x2 inch) loaves; place on a broiler pan coated with cooking spray. Bake for 15 minutes at 425 degrees. After 15 minutes, spoon the glaze evenly over each meatloaf. Bake an additional 10 minutes until done.