Total Time
1hr 30mins
Prep 10 mins
Cook 1 hr 20 mins

Here is the mother recipe for hundreds of casseroles! Just mix and match the ingredients. Use your creativity! :) Be diabolical >:) From southernliving.com

Ingredients Nutrition

  • 2 cups meat (see description)
  • 2 cups cream soup, sauce (or alternative, see description)
  • 1 (3 ounce) can mushrooms (or alternative, see description)
  • 2 cups vegetables (see description)
  • 2 cups uncooked rice or 2 cups pasta
  • 1 cup cheese (see description) or 1 cup bread or 1 cup cracker crumb
  • 1 (8 ounce) container sour cream
  • 1 cup milk
  • 1 teaspoon salt
  • 1 teaspoon pepper

Directions

  1. The meat can be: 2 cans tuna, shrimp or crab, or 2 cups chopped cooked chicken or turkey, or 2 cups chopped ham, or 1 lb. ground beef, cooked crumbled and drained.
  2. The sauce can be: 1 can of cream of "your favorite, I like onion" soup or 2 cans (14 1/2 oz) tomatoes or 2 cups of your own sauce (barbecue, sweet and sour, teriyaki, curry, marinara, gravy, cheese sauce, use your imagination).
  3. The extra can be: 1 small can mushrooms, 1 small can sliced olives, 1/4 cup chopped red or green bell pepper, 1/4 cup chopped onion, 1/4 cup chopped celery, 2 minced garlic cloves, 1 can chopped green chilies, 1 package taco seasoning etc etc.
  4. The vegetable can be: 1 14-1/2 ounce can vegetable of your choice (peas, green beans, spinach, corn, asparagus) or 2 cups frozen or fresh.
  5. The starch can be: uncooked small pasta shells, egg noodles, uncooked rice, etc etc.
  6. You can use one or two toppings: 1/2 cup cheese of any kind, or 1 cup bread/cracker crumbs mixed with melted butter and sprinkled on top, or stuffing mix. Could be crushed taco or potato chips. Or French fried onions. Just think of something crunchy ;).
  7. Once you have chosen your diabolical combination, combine 1 8-ounce container sour cream, 1 cup milk, 1 cup water, 1 tsp salt and 1 tsp pepper with sauce (omit sour cream and milk if using tomatoes).
  8. Stir in Vegetable, Pasta/Rice, Meat/Fish/Poultry, and, if desired, Extras. Spoon into a lightly greased 13- x 9-inch baking dish. Bake, covered, at 350? for 1 hour and 10 minutes. Uncover and sprinkle with Toppings; bake 10 more minutes.
  9. I know I may get some flak for this recipe, as there is so much room for variable, and therefore margin for error, so I hope readers will be open-minded when rating this recipe, it is a general guideline for what amounts of each ingredient - I can't take responsibility for your choice of ingredients! :).
Most Helpful

Years ago I had this page from Southern Living torn out and posted on the inside of a cabinet door for easy reference. Too many moves and I lost it, but I'm so happy to find this again online! Thank you SO MUCH for posting it. I remember always adding about 1/4-1/2 cup more milk or broth every time because without the extra liquid it becomes very dense/sticky and even more dry on reheat. But that's my only addition - this recipe is so simple and flexible! Though these days I'll probably use plain greek yogurt in place of the sour cream. :)

greenie-green November 06, 2015

Awesome recipe !!! I've tried it several times, varying ingredients each time and it's always a hit at my house. Thanks so much for sharing.

lub2cook July 01, 2010